Positive Marijuana Research Database
Intervertebral disc degeneration is a major contributor to low back pain worldwide. It involves a process of inflammation with alterations to nerve, oxygen, and water levels and increased cell destruction among others. Cannabidiol is a cannabis sativa (marijuana) component with anti-inflammatory and protective benefits. In this study, rats received a disc puncture, followed by an […]
The effectiveness of vaporized cannabis (marijuana) was evaluated in these 8 hour human laboratory experiments. Following baseline evaluation, 42 participants experiencing neuropathic pain due to injury or disease of the spinal cord were given 4 puffs of either placebo or 2.9% or 6.7% THC. A second dosing was given 3 hours later, at which time […]
Patients with spinal cord injury experience severe bone loss below the level of spinal injury. The aim of this study was to determine if one of the non-psychoactive components (CBD) of marijuana would have a positive effect. Adult male rats with a surgical cutting of the spinal cord were treated for 14 consecutive days with […]
In order to determine whether plant-derived cannabis medicinal extracts (CME) can alleviate nerve pain symptoms unresponsive to standard treatment, a consecutive series of double-blind, randomized, placebo-controlled single-patient cross-over trials with two-week treatment periods was performed. 18 patients with multiple sclerosis, 4 with spinal cord injury, 1 with brachial plexus damage, and 1 with limb amputation […]
Many nations in the western world have recently been revising their laws on the medical use of cannabis (marijuana). In Switzerland the Department of Health has been granting special permission for marijuana and cannabinoids. In this Swiss analysis, the authors acknowledge that some randomized controlled trials have shown a good efficacy for spasticity associated with […]
Multiple sclerosis is an autoimmune disease leading to the destruction of myelin and nerve degeneration resulting in severe physical debilitation. Myelin surrounds the nerve similar to plastic surrounding an electrical wire. The disease can be treated with immunosuppressive drugs that alleviate the symptoms and slow disease aggravation. One of those drugs currently in clinical use […]