Intervertebral disc degeneration is a major contributor to low back pain worldwide. It involves a process of inflammation with alterations to nerve, oxygen, and water levels and increased cell destruction among others.
Cannabidiol is a cannabis sativa (marijuana) component with anti-inflammatory and protective benefits. In this study, rats received a disc puncture, followed by an injection of cannabidiol into the injured disc.
The cannabidiol significantly reduced the effects of the disc injury and could be useful in the treatment of intervertebral disc degeneration.
