Many nations in the western world have recently been revising their laws on the medical use of cannabis (marijuana). In Switzerland the Department of Health has been granting special permission for marijuana and cannabinoids.
In this Swiss analysis, the authors acknowledge that some randomized controlled trials have shown a good efficacy for spasticity associated with multiple sclerosis and following spinal cord injuries. They also note there are positive studies for neuropathic and cancer pain as well.
They also mention that cannabinoid safety is is considered good, and state that severe psychiatric effects are very rare and can be avoided if contraindications are respected.