This double-blind, placebo-controlled crossover study was performed to determine the effects of cannabis (marijuana) doses on neuropathic pain uncontrolled by conventional medications.
Neuropathic pain is considered to be maladaptive because “the pain neither protects nor supports healing and repair. This means there’s no reason to “tough it out”. Typical synthetic medicines give only partial relief to only half of those patients, leaving many without pain relief.
It was found that low dose (1.29% THC) vaporized cannabis was essentially as effective as medium dose (3.53% THC) cannabis for providing pain relief. Even low doses of THC may offer relief to some patients who do not respond to typical pharmaceuticals for neuropathic pain.
