In this prospective trial, 21 Crohn’s disease patients with an average age of 40 who had not responded to therapy with steroids, immunomodulators, or anti-tumor necrosis factor-α agents, were studied.
Ten out of the eleven patients who were treated by smoking cannabis twice daily with 115 mg of THC each session over the course of 8 weeks achieved significant clinical, steroid-free benefits without side effects.