Reports of the use of extracts from the cannabis (marijuana) plant being applied topically to open cutaneous wounds, for the purposes of promoting wound healing and relieving wound-related pain, date back to antiquity.
Pyoderma gangrenosum (PG) is a rare inflammatory neutrophilic skin disease, that classically presents as cutaneous ulcerations which most commonly occur on the lower extremities. It is important to note that it is frequently misdiagnosed as cellulitis, venous leg ulcers, and arterial ulcers.
In this study, 3 case studies of PG patients treated with a topical medical cannabis compounded in non-genetically modified organic sunflower oil are reported on. Clinically significant analgesia (pain relief) of at least 30% that was associated with reduced opioid use was noted in all 3 cases.
