In order to assess the effectiveness of cannabis (marijuana) preparations for relieving pain in patients with malignant diseases, a comprehensive search of the literature up to 2017 was conducted.
18 predominantly double-blind trials were chosen which compared effectiveness of cannabis to placebo. 15 of the 18 trials demonstrated that cannabis had a significant effect, with 43% of those after two weeks of treatment reporting a 30% or greater reduction on pain.
Interestingly, the authors of this study stated that the target dose for relieving pain in patients with malignant disease seemed to be 10 “actuations” (number of times in day administered) with a total of about 27 mg of THC, and about 25 mg of CBD. (Please note that is approximately 2.5 mg per administration.)
Two considerations should be noted. First, it is wise to “start low and go slow” as discussed in this MMJINTHEUSA article, before potentially reaching that level of daily THC. Secondly, the near similar levels of THC and CBD may demonstrate that using whole plant leaf could be of greater benefit than individual extractions where one is significantly greater than the other.
Individuals should consult their medical providers for specifics regarding their medical marijuana. It is generally considered that your individual effective dose is the smallest amount necessary to achieve the result.
