Positive Marijuana Research Database
The theory of clinical endocannabinoid deficiency was published in 2001. It was based on the concept that many brain disorders are associated with neurotransmitter deficiencies, and that a similar scenario could be at play in the endocannabinoid system, which would then manifest as certain disorders. The endocannabinoid system was named after the cannabis (marijuana) plant, […]
Management of chronic pain is one of the most common reasons for seeking marijuana (cannabis) medicine. However little is known regarding the effects of combining marijuana and prescription pain medicines on the potential for more serious alcohol and other substance involvement. This article collected data on 273 participants in southwestern Michigan with comparisons on socio-demographics, […]
Even though there is little evidence that they are effective for the long term, chronic pain patients are commonly treated with opioids. The purpose of this study was to determine if using medical cannabis (marijuana) for chronic pain changed individual patterns of opioid use. A survey of 244 medical marijuana patients with chronic pain was […]
It is well documented that marijuana (cannabis) is regularly and effectively used for pain mitigation. But its other benefits are often surprising. In this study it was found that cannabis sativa (marijuana) extracts rich in THC can protect the mucosal lining of the stomach. One method of protection is that marijuana seems to inhibit stomach […]
The effectiveness of vaporized cannabis (marijuana) was evaluated in these 8 hour human laboratory experiments. Following baseline evaluation, 42 participants experiencing neuropathic pain due to injury or disease of the spinal cord were given 4 puffs of either placebo or 2.9% or 6.7% THC. A second dosing was given 3 hours later, at which time […]
In the world of pain relief, men and women sometimes respond slightly differently to any given medicine or intervention. This analysis under double-blind, placebo controlled conditions, set out to determine what differences marijuana (cannabis) might have on men vs. women. Active cannabis (marijuana) with a THC level of 3.5-5.6% was compared with inactive cannabis with […]
In this Canadian study of 271 medical marijuana patients, results were similar to that found for dispensary patients in New England, where many were able to reduce prescription medication. Cannabis (marijuana) is perceived to be an effective treatment for many diverse conditions, including pain and mental health, and 63% of these patients substituted marijuana for […]
Significant rates of depression and anxiety are consistently reported among patients with chronic pain. Since medical marijuana (cannabis) has become more prevalent for treatment of chronic pain, this cross sectional study compared depression among opioid users, marijuana users, and those who used both. Depression rates in opioid users was 57%, for marijuana users 22%, and […]
In order to determine whether plant-derived cannabis medicinal extracts (CME) can alleviate nerve pain symptoms unresponsive to standard treatment, a consecutive series of double-blind, randomized, placebo-controlled single-patient cross-over trials with two-week treatment periods was performed. 18 patients with multiple sclerosis, 4 with spinal cord injury, 1 with brachial plexus damage, and 1 with limb amputation […]
Reports of the use of extracts from the cannabis (marijuana) plant being applied topically to open cutaneous wounds, for the purposes of promoting wound healing and relieving wound-related pain, date back to antiquity. Pyoderma gangrenosum (PG) is a rare inflammatory neutrophilic skin disease, that classically presents as cutaneous ulcerations which most commonly occur on the […]